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Nanowires make drugs stick
The silicon-nanowire-coated beads adhere better to mucous membranes than non-coated beads. The nanowires increase the force required to lift the beads from a mucous membrane by as much as 100 times.
The beads could be used to improve the uptake of drugs delivered through mucous membranes.
Research paper:
Biomimetic Nanowire Coatings for Next Generation Adhesive Drug Delivery Systems
Nano Letters, published online January 21, 2009
Researchers' homepages:
Benjamin J. Alema´n
Alex Zettl
Tejal A. Desai
Back to TRN February 2/9, 2009
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